Humira is a drug that can relieve pain and reduce inflammation in individuals with several autoimmune diseases. Its generic name is adalimumab.
Doctors prescribe Humira to treat rheumatoid arthritis, chronic plaque psoriasis, Crohn’s disease, ankylosing spondylitis, psoriatic arthritis, polyarticular juvenile idiopathic arthritis, and non-infectious uveitis.
Humira is really a biologic drug. Scientists frequently make biologics using protein antibodies from an income organism, such for example, humans, animals, microorganisms, or yeast.
They produce proteins using DNA technology. It is a kind of genetic engineering.
People normally take Humira at home, employing a syringe or even a pen device that already provides the medication. They cannot take it by mouth since the human gastrointestinal system would destroy the active ingredient.
How it works
Within an autoimmune disease, your body’s immunity system falsely detects and attacks a threat within the organization that will not exist.
This will lead to many problems and conditions, including rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, Crohn’s disease, and psoriasis.
Experts are unsure exactly what causes autoimmune diseases, but tumor necrosis factor-alpha (TNFα) appears to be always a significant contributor to inflammation in these diseases.
TNFα triggers inflammation when the body is under threat, and the immunity system goes into action to protect it.
However, too much TNFα can attack healthy tissue and cause inflammation. Inflammation can lead to pain.
Humira Cost binds to TNFα and blocks its inflammatory effect. This reduces pain and inflammation in individuals with autoimmune diseases.
The word HUMIRA stands for Human Monoclonal Antibody In Rheumatoid Arthritis.
Clinical trials show that Humira is effective in treating a range of auto-immune diseases. It’s approval for these conditions.
Active ankylosing spondylitis
This is a chronic inflammation of the spine and sacroiliac joints. The patient feels pain and stiffness in and around the region of the spine. Eventually, chronic inflammation can lead to a complete fusion of the vertebrae. The name of this process is ankylosis.
Ankylosing spondylitis sometimes occurs in individuals with inflammatory bowel disease, such as example, ulcerative and Crohn’s colitis, and psoriasis.
In 2007, an evidence-based review suggested that Humira is effective in treating ankylosing spondylitis. The researchers described its use as “cost-effective.”
Moderate to severe chronic plaque psoriasis
Around 80 percent of patients with psoriasis have this kind of psoriasis, following the National Institutes of Health (NIH).
Symptoms include well-defined patches of red raised skin, usually on the trunk, scalp, elbows, knees, and nails, however, the patches can appear anywhere on the skin. Scale builds through to the top of plaques.
Individuals with psoriasis have dehydrated skin that can itch, crack, and be painful.
In July 2016, the Decision Resources Group (DRG) noted that Humira and similar biologics are continuing to get popularity as a cure for psoriasis.
Moderate to severe psoriatic arthritis
This problem contributes to joint inflammation. The NIH remember that joint inflammation affects about 20 percent of individuals with psoriasis.
Doctors commonly prescribe Humira to treat psoriatic arthritis, but researchers remain to investigate the most effective ways to make use of it.